Treatment

Long-Acting Nitroglycerin

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Nitroglycerin eases chest pain (angina) by getting more blood and oxygen to your heart. It also works by reducing the heart's need for oxygen by dilating the arteries. Long-acting nitroglycerin helps prevent angina from starting.

To prevent angina

If you use a patch:

  • Remove the old patch. Then apply a new one to a clean, dry place on the chest or upper arm.

  • Pick a new place each time you change the patch.

  • Don't put the patch where skin is hairy, cut, irritated, scarred, or tattooed.

If you use a tablet or capsule:

  • Take the tablet or capsule 1 hour before or 2 hours after eating.

  • Swallow it with a glass of water. Don't break, chew, or crush the tablet or capsule.

If you use an ointment:

  • Measure the prescribed amount of ointment onto the paper that comes with it.

  • Spread a thin, even layer on a clean patch of skin. Don't rub it in. Tape the paper in place with skin tape for as long as instructed, then remove it. 

  • Use a new spot each time you apply the paste.


 Precautions

  • Don't suddenly stop using nitroglycerin to prevent angina. This could cause an angina attack. Check with your healthcare provider first.

  • Limit the amount of alcohol you drink. Too much alcohol can cause dizziness or fainting.

  • Tell your healthcare provider about any medicines, supplements, or herbs you use. Nitroglycerin can interact with other medicines and cause serious problems. 

  • Don't take phosphodiesterase inhibitors such as sildenafil (Viagra). These are medicines that help sexual function in men but are very dangerous if taken any time if you are on nitroglycerin.

  • Check the expiration date. Nitroglycerin can lose its effectiveness over time. Nitroglycerin must be protected from both heat and light.

Call your healthcare provider right away if you have:

  • Chest pain that lasts longer, is different or more severe, or occurs more often

  • Irregular heartbeat

  • Shortness of breath

  • Blurred vision

  • Dizziness or you pass out

  • Severe headache

Online Medical Reviewer: Glenn Gandelman MD MPH

Online Medical Reviewer: John Hanrahan MD

Online Medical Reviewer: Lu Cunningham RN BSN

Date Last Reviewed: 12/01/2022

© 2000-2025 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.

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