Treatment

Preventing Bleeding During Chemotherapy

Choose a preferred language

Chemotherapy can make your blood less able to clot. This is because it lowers the number of clotting cells (platelets) in your blood. As a result, your risk of bruising and bleeding goes up. To help prevent problem bleeding, use the tips on this handout.


Know what to expect

Some types of chemotherapy cause more bleeding problems than others. Your risk of bleeding increases over the course of treatment. Your risk is greatest during the period in each treatment cycle when your platelet count is lowest. This is called the nadir. Talk with your healthcare provider about your nadir. Then take extra care to prevent bleeding at that time.


Preventing bleeding and bruising

  • When brushing your teeth, use a soft toothbrush. If flossing or using a dental water jet causes bleeding, stop until your platelet count increases.

  • Talk to your dentist about postponing teeth cleanings or dental work.

  • Shave with an electric razor, not a straight razor.

  • Ask your healthcare provider which medicines you should stop taking. Anti-inflammatory medicines such as aspirin, naproxen, or ibuprofen make it harder for blood to clot. Talk with your healthcare provider about all the medicines you take. This includes over-the-counter medicines, vitamins, supplements, and herbs.

  • Eat a high-fiber diet or take a stool softener to prevent constipation. Straining at stool can cause bleeding in your anus.

  • Don't do contact sports or other activities likely to cause bruising.

  • Don't use tampons, suppositories, or enemas.

  • Protect your skin from cuts, scrapes, and sharp objects.

  • Don't blow your nose or cough with great force.

  • Keep your home safe to prevent injuries and falls.


When to call your healthcare provider

Call your healthcare provider right away if you have:

  • Blood in your urine or stool

  • Easy bruising 

  • Small red spots under your skin

  • Bleeding that won’t stop, such as from your gums or nose

  • Menstrual flow that is heavy or lasts longer than normal

  • Vomiting

  • Vision changes

  • Frequent headaches

Featured in

Online Medical Reviewer: L Renee Watson MSN RN

Online Medical Reviewer: Rita Sather RN

Online Medical Reviewer: Todd Gersten MD

Date Last Reviewed: 12/01/2021

© 2000-2025 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.

Find a doctor that's right for you.

From routine check-ups to groundbreaking treatments and beyond, Crestner Health is here to help you live your healthiest life.

Search our doctors
Related Articles
Read article
Oncology
Parotidectomy

The parotid is a gland near the ear. It helps make and control the release of saliva. If a tumor forms in the parotid gland, it can press on the facial nerve, causing discomfort and pain. Part or all of the face may be weak or paralyzed. To treat a parotid tumor, part or all of the gland is removed. This surgery is called parotidectomy. This sheet explains the surgery and what to expect.

Read article
Oncology
Transoral Resection for Oral Cancer

Transoral resection is surgery to help control or cure oral cancer. During surgery, an oral tumor is removed through the mouth. This sheet explains transoral resection and what to expect.

Read article
Oncology
Acute Lymphocytic Leukemia: Targeted Therapy

Targeted therapy is the use of medicines that take aim on parts of cancer cells that make them different from healthy cells.

Read article
Oncology
Targeted Therapy for Cancer

Targeted therapy uses medicines that are aimed at the cancer cell specifically. Because of this, targeted therapy may cause fewer side effects. There are many kinds of targeted therapy medicines. They work differently on different types of cancers.