Nitroglycerin eases chest pain (angina) by getting more blood and oxygen to your heart. It also works by reducing the heart's need for oxygen by dilating the arteries. Long-acting nitroglycerin helps prevent angina from starting.
To prevent angina
If you use a patch:
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Remove the old patch. Then apply a new one to a clean, dry place on the chest or upper arm.
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Pick a new place each time you change the patch.
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Don't put the patch where skin is hairy, cut, irritated, scarred, or tattooed.
If you use a tablet or capsule:
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Take the tablet or capsule 1 hour before or 2 hours after eating.
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Swallow it with a glass of water. Don't break, chew, or crush the tablet or capsule.
If you use an ointment:
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Measure the prescribed amount of ointment onto the paper that comes with it.
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Spread a thin, even layer on a clean patch of skin. Don't rub it in. Tape the paper in place with skin tape for as long as instructed, then remove it.
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Use a new spot each time you apply the paste.
Precautions
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Don't suddenly stop using nitroglycerin to prevent angina. This could cause an angina attack. Check with your healthcare provider first.
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Limit the amount of alcohol you drink. Too much alcohol can cause dizziness or fainting.
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Tell your healthcare provider about any medicines, supplements, or herbs you use. Nitroglycerin can interact with other medicines and cause serious problems.
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Don't take phosphodiesterase inhibitors such as sildenafil (Viagra). These are medicines that help sexual function in men but are very dangerous if taken any time if you are on nitroglycerin.
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Check the expiration date. Nitroglycerin can lose its effectiveness over time. Nitroglycerin must be protected from both heat and light.
Call your healthcare provider right away if you have:
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Chest pain that lasts longer, is different or more severe, or occurs more often
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Irregular heartbeat
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Shortness of breath
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Blurred vision
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Dizziness or you pass out
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Severe headache