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Recovery

Managing Post-Op Pain at Home: Medicines

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Pain after an operation (post-op pain) is common and expected. These guidelines can help you stay as comfortable as possible.

Woman reading instructions on prescription pill bottle.


Taking pain medicines

  • Take only the medicines that your health care provider tells you to take.

  • Don't take more than prescribed. Don't take your next dose sooner than prescribed.

  • Take pain medicines with some food to prevent an upset stomach.

  • Don’t drink alcohol while using pain medicines.

  • Don't drive while taking opioid pain medicines. 


Types of pain medicines

Non-opioid

  • Check with your health care provider before you take any over-the-counter (OTC) pain reliever in addition to or instead of your prescribed pain medicine.

  • Non-opioids include OTC acetaminophen and ibuprofen and some prescription pain relievers.

  • All relieve mild to moderate pain. Some reduce swelling.

  • Possible side effects include stomach upset and bleeding. High doses may cause kidney or liver problems.

Opioid

  • Opioids are available only by prescription.

  • Opioids ease moderate to severe pain.

  • Possible side effects include stomach upset, nausea, drowsiness, rash, and itching.

  • Opioids may cause constipation. To help prevent this, eat high-fiber foods and drink plenty of water.

  • Your health care provider may recommend a stool softener.

  • Don't drive, make important decisions, or operate machinery while taking opioids.


When to call your doctor

Contact your health care provider or seek medical attention right away if you:

  • Have nausea, vomiting, diarrhea, constipation, or stomach cramps.

  • Have breathing problems or a fast, racing heart rate. (Call 911.)

  • Feel tired, sluggish, or dizzy.

  • Have a skin rash or other allergic symptoms.

  • Have pain that is not eased with the pain medicine.

© 2000-2025 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.

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